Product Description
Artesunate and amodiaquine table , sold under the brand name Dmscarepharma among others, is a medication used for the treatment of malaria. It is a fixed-dose combination of artesunate and amodiaquine. Specifically it recommended for acute uncomplicated Plasmodium falciparum malaria. It is taken by mouth.
Common side effects include loss of appetite, nausea, abdominal pain, sleepiness, trouble sleeping, and cough. Safety in pregnancy is not clear; however, the medication may be used if others are not possible. It is believed to be safe for use during breastfeeding. Artesunate and amodiaquine are both antimalarial medication; however, work by different mechanisms.
Package:
- Artesunate and Amodiaquine(25 mg +67.5 mg) base tablet blister pack of 3 tablets*1 /box,
- Artesunate and Amodiaquine(50 mg +135 mg) base tablet blister pack of 3 tablets*1 /box ,
- Artesunate and Amodiaquine(100 mg +270 mg) base tablet blister pack of 3 tablets*1 /box ,
- Artesunate and Amodiaquine (200mg+600mg) base tablet blister pack of 6 tablets/blister*1 /box ,
Indications
Treatment of uncomplicated falciparum malaria
Treatment of uncomplicated malaria due to other Plasmodium species, when chloroquine cannot be used
Completion treatment following parenteral therapy for severe malaria
Dosage and duration
|
Weight |
Tablets |
D1 |
D2 |
D3 |
|
4.5 to < 9 kg |
25 mg +67.5 mg |
1 tab |
1 tab |
1 tab |
|
9 to < 18 kg |
50 mg +135 mg |
1 tab |
1 tab |
1 tab |
|
18 to < 36 kg |
100 mg +270 mg |
1 tab |
1 tab |
1 tab |
|
≥ 36 kg |
200 mg +600 mg |
1 tab |
1 tab |
1 tab |
Artesunate is a medication for treating malaria. The intravenous form is preferred over quinine for severe cases. It’s often used in combination therapy, like artesunate plus mefloquine. It isn’t used for malaria prevention. Artesunate can be administered by vein injection, muscle injection, orally, or rectally.
Amodiaquine is a drug for treating malaria, including uncomplicated Plasmodium falciparum malaria. It’s recommended to be given with artesunate to lower the risk of resistance. Due to the risk of rare but serious side effects, it’s not generally advised for malaria prevention. However, the World Health Organization (WHO) recommended its use for seasonal prevention in high-risk children in combination with sulfadoxine and pyrimethamine in 2013.