Ertugliflozin Tablets 15 mg

What is ertugliflozin?

Ertugliflozin is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Ertugliflozin is not for treating type 1 diabetes.

Ertugliflozin may also be used for purposes not listed in this medication guide.

Before taking this medicine

You should not use ertugliflozin if you are allergic to it, or if you have:

• severe kidney disease (or if you are on dialysis).

Ertugliflozin may increase your risk of lower leg amputation, especially if you have had a prior amputation, a foot ulcer, heart disease, circulation problems, or nerve damage.

Tell your doctor if you have ever had:

• heart problems;
• a diabetic foot ulcer or amputation;
• circulation problems or nerve problems in your legs or feet;
• liver or kidney disease;
• bladder infections or other urination problems;
• low blood pressure;
• diabetic ketoacidosis;
• problems with your pancreas, including surgery;
• if you drink alcohol often;
• if you have a planned surgery;
• if you have type 1 diabetes; or
• if you are on a low salt diet.

Follow your doctor’s instructions about using ertugliflozin if you are pregnant. Blood sugar control is very important during pregnancy, and your dose needs may be different during each trimester.

You should not use ertugliflozin during the second or third trimester of pregnancy.

You should not breastfeed while using ertugliflozin.

How should I take ertugliflozin?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

You may take ertugliflozin with or without food.

Call your doctor if you are sick with vomiting or diarrhea, if you consume less food or fluid than usual, or if you are sweating more than usual.

Your blood sugar will need to be checked often, and you may also need to test the level of ketones your urine. Ertugliflozin can cause life-threatening ketoacidosis (too much acid in the blood). Even if your blood sugar is normal, contact your doctor if a urine test shows that you have ketones in the urine.

Low blood sugar (hypoglycemia) can happen to everyone who has diabetes. Symptoms include headache, hunger, sweating, irritability, dizziness, nausea, fast heart rate, and feeling anxious or shaky. To quickly treat low blood sugar, always keep a fast-acting source of sugar with you such as fruit juice, hard candy, crackers, raisins, or non-diet soda.

Your doctor can prescribe a glucagon emergency injection kit to use in case you have severe hypoglycemia and cannot eat or drink. Be sure your family and close friends know how to give you this injection in an emergency.

Also watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination, blurred vision, headache, and tiredness.

Blood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.

This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using ertugliflozin.

Ertugliflozin is only part of a treatment program that may also include diet, exercise, weight control, regular blood sugar testing, and special medical care. Follow your doctor’s instructions very closely.

Store at room temperature away from moisture and heat. Keep unused tablets in the foil blister pack in its original container.

Ertugliflozin dosing information

Usual Adult Dose for Diabetes Type 2:

Initial dose: 5 mg orally once a day in the morning
-May increase to 15 mg orally once a day for patients tolerating therapy and requiring additional glycemic control
Maximum dose: 15 mg per day

Comments:
-Volume depletion should be corrected prior to initiating therapy.
-This drug is not recommended for patients with type 1 diabetes mellitus; it may increase the risk of diabetic ketoacidosis in these patients.

Use: An adjunct to diet and exercise to improve glycemic control in adults with Type 2 diabetes mellitus.